In reference to previous post titled "Exchange Server 2007 Transport: 452 4.3.1 Insufficient system resources", the Back Pressure feature, that detects resource pressure on Exchange Server 2007 transport servers and stops accepting new message submission if low on resources, can be turned off.
Here's how to do it:
1. Open the EdgeTransport.exe.config file from \Exchange Server\bin directory using notepad
2. Add the following key+value pair:
add key="EnableResourceMonitoring" value="false"
3. Save file
4. Restart Microsoft Exchange Transport Service (MSExchangeTransport)
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